Galapagos extends target
discovery alliance with Cystic Fibrosis Foundation Therapeutics
Mechelen, Belgium and
Bethesda, Maryland, USA; 22 November 2006 – Galapagos
NV (Euronext & LSE: GLPG) announced today the extension
of the target discovery alliance between its service division
BioFocus DPI and Cystic Fibrosis Foundation Therapeutics,
Inc. (CFFT), the drug discovery and development affiliate
of the Cystic Fibrosis Foundation. This 15-month extension
exceeds €800,000 in research fees and builds further
on the alliance initiated in April 2005. As recently presented
at the 20th Annual North American Cystic Fibrosis Conference
in Denver, BioFocus DPI is applying its SilenceSelect adenoviral
library and expertise in assay design to discover novel
drug targets for the development of new cystic fibrosis
therapies.
“The project to discover
novel targets for cystic fibrosis is proceeding very well,
and we are therefore pleased and proud that Cystic Fibrosis
Foundation Therapeutics has extended the alliance. This
will enable BioFocus DPI to deliver validated targets as
the basis for the development of new medicines,” said
Onno van de Stolpe, Chief Executive Officer of Galapagos.
“It is particularly gratifying that our target discovery
engine is being applied to the unmet medical needs addressed
by patient foundations such as the Cystic Fibrosis Foundation.”
“We are pleased with
the quality of the results achieved to date in the alliance.
BioFocus DPI’s innovative target discovery platform
is poised to deliver promising targets for the treatment
of cystic fibrosis," said Robert J. Beall, Ph.D., president
and CEO of the Cystic Fibrosis Foundation. “Our interactions
with this team have been very positive and bode well for
a successful outcome of this alliance.”
About Cystic Fibrosis
Cystic fibrosis (CF) is a genetic
disease affecting approximately 30,000 children and adults
in the United States alone. A defective gene causes the
body to produce abnormally thick, sticky mucus that blocks
the airways, leading to life-threatening lung infections,
and that obstructs the pancreas, causing difficulty absorbing
food. The median life expectancy of CF patients has improved
from early childhood to the mid-30s today, but many individuals
battle lung disease for years.
About the Cystic Fibrosis
Foundation and CFFT
The mission of the Cystic Fibrosis
Foundation is to assure the development of the means to
cure and control CF and to improve the quality of life for
those with the disease. With money raised through donations
from individuals, corporations and foundations since its
establishment in 1955, the CF Foundation supports research
and care to continue adding tomorrows every day to the lives
of those with CF.
CFFT is the non-profit drug discovery and development affiliate
of the CF Foundation. CFFT supports and governs activities
related to CF drug discovery through drug development and
clinical evaluation. The CF Foundation provides support
to fund CFFT's operations, specifically the Therapeutics
Development Program. For more information about CF, the
Cystic Fibrosis Foundation or CFFT, visit www.cff.org.
About Galapagos
Galapagos is a publicly traded, genomics-based drug discovery
company (Euronext Brussels, GLPG; Euronext Amsterdam, GLPGA,
London AiM: GLPG) that has drug discovery programs based
on proprietary, novel targets in bone and joint diseases
- osteoarthritis, osteoporosis and rheumatoid arthritis.
Galapagos offers a full suite of target-to-drug discovery
products and services to pharmaceutical and biotech companies
through its division BioFocus DPI, encompassing target discovery
and drug discovery services through to delivery of pre-clinical
candidates. In addition, BioFocus DPI provides adenoviral
reagents for rapid identification and validation of novel
drug targets and compound libraries for drug screening.
Galapagos currently employs more than 330 people, including
144 PhDs, and operates facilities in seven countries, with
global headquarters in Mechelen, Belgium. More information
about Galapagos and BioFocus DPI can be found at www.glpg.com.
CONTACT
Galapagos NV
Onno van de Stolpe, CEO
Tel: +31 6 2909 8028
ir@glpg.com
Cystic Fibrosis Foundation
Suzanne Pattee
VP, Public Policy and Patient Affairs
Tel: +1 301 907 2548
spattee@cff.org
Laurie Fink
Director of Media Relations
Tel: +1 301 841 2602
lfink@cff.org
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