Leiden,
The Netherlands, May 13, 2003. Galapagos Genomics, the Netherlands/Belgian
functional genomics company, today announced the launch
of their human full-length gene adenoviral expression library
under the name FLeXSelect™. FLeXSelect has been jointly
developed with Incyte Corporation and contains over 1,200
fully sequence verified, mainly drugable, human genes, many
of whose functions are unknown. The arrayed adenoviral library
is ideal for gene function discovery and validation in in-vitro
and in-vivo assays of disease phenotypes. Galapagos is responsible
for marketing and sales of FLeXSelect worldwide, offering
access either through a success based, risk-sharing program
or on a pure fee for service basis.
“We
are happy that Incyte has made this valuable collection
of largely un-annotated human genes available to the research
community. We are convinced that in combination with Galapagos’
proven adenoviral expression technology it will not be long
before a substantial set of the genes in FLeXSelect will
be functionally annotated”, said Onno van de Stolpe,
CEO of Galapagos. “In combination with phenotypic
assays based on disease relevant models, finding those genes
that can modulate the disease phenotype has never been easier.”
“We
are pleased to collaborate with Galapagos Genomics in exploiting
our extensive collection of full-length genes,'' said Robert
Stein, MD, PhD, President and CSO of Incyte. ``The technology
platform that Galapagos has developed is extremely useful
in delineating the functions of novel genes and assisting
in the exploration of targets for drug discovery.”
Galapagos
Genomics is a privately held company headquartered in Mechelen,
Belgium. The Company has built a functional genomics platform
using arrayed adenoviruses containing human genes. Its PhenoSelect
libraries are in a format that enables high-throughput screening
using cellular assays. Galapagos is using its technology
platform for the discovery and validation of proprietary
drug targets and for partnering with biotech and pharma.
Its proprietary research programs focus on Alzheimer, bone
diseases and psoriasis. The Company currently employs 92
people, including 23 PhD's, and occupies a 15,000 sq.f.
research and production facility in Mechelen, with additional
research laboratories in Leiden, The Netherlands. In addition
to Incyte, Galapagos’ current partners include Bayer,
Degussa, Euroscreen, Exelixis, J&J, Organon, Pharmacia,
Vertex and UCB. The shareholders are Abingworth Management,
Apax Partners, Burrill & Company, NIB Capital Private
Equity, Crucell Holland BV (Nasdaq, Euronext: CRXL) and
Tibotec-Virco NV. Galapagos' web address is www.galapagosgenomics.com.
For additional information on Incyte, an emerging drug discovery
company and a leading provider of genomics-based information
products designed to support the discovery of new drugs
and diagnostics, please go to www.incyte.com
Contact details:
Galapagos Genomics
Onno van de Stolpe
CEO
Phone:
+32 15 342 900