Mechelen,
Belgium and Freising, Germany, April 7, 2003. Galapagos
Genomics NV, the Belgian functional genomics company, and
Degussa BioActives announced today that they have entered
into a research collaboration to identify nutraceuticals
beneficial in joint health management.
Under
the agreement, Galapagos will design human cellular assays
measuring key biological processes. This includes assay
development, screening of libraries of natural compounds,
and validation of identified leads with focus on the field
of arthritis. Degussa has exclusive rights to commercialize
nutraceuticals that result from this research collaboration.
Galapagos is eligible for milestone payments and royalties
on the commercialization of these products.
"The
unique combination of Galapagos' human cellular disease
models with Degussa's expertise in bioactives has high potential
to identify new ingredients with proven health benefits.
We are very pleased that Degussa has decided to work with
Galapagos for its expertise in joint/bone related diseases,
one of our core areas," said Onno van de Stolpe, CEO
of Galapagos. "This is our first agreement in the nutraceutical
field and with a strong development and marketing partner
like Degussa BioActives, this new collaboration has the
potential to become an important income generator for Galapagos."
"Galapagos'
success in identifying and validating disease relevant gene
functions using human cellular assays, has convinced us
that they are an outstanding partner to identify food ingredients
that have beneficial effects in the field of arthritis"
said Dr. Hans-Ullrich Hoppe, Degussa BioActives' Vice President,
Research and Development. "This collaboration will
allow Degussa BioActives to utilize its libraries in a very
beneficial way. We are very optimistic to identify good
hits which can be used as nutraceuticals and contribute
to Degussa's strong position worldwide in that growing market."
Galapagos
Genomics is a privately held company headquartered in Mechelen,
Belgium. The Company has built a functional genomics platform
using arrayed adenoviruses containing human gene sequences.
It's knock-in PhenoSelect and knock-down SilenceSelect collections
are in an arrayed format that enables high-throughput screening
using cellular assays. Galapagos is using its technology
platform for the discovery and validation of proprietary
drug targets and for partnering with biotechnology and pharmaceutical
companies. It's research programs focus on three disease
areas: Alzheimer's disease, bone/joint diseases and psoriasis.
The Company currently employs 92 people, including 22 PhD's,
and occupies a 2000 sq.m. research and production facility
in Mechelen, with additional research laboratories in Leiden,
The Netherlands. Galapagos' current partners include Bayer,
Euroscreen, Exelixis, Incyte, Johnson&Johnson, Organon,
Pharmacia, Procter&Gamble, UCB Pharma and Vertex. The
shareholders are Abingworth Management, Apax Partners, Burrill&Company,
NIB Capital Private Equity, Crucell Holland BV (Nasdaq,
Euronext: CRXL) and Tibotec-Virco NV. Galapagos' web address
is www.galapagosgenomics.com.
Represented
with sales offices and R&D centers in Europe, Asia and
the US Degussa BioActives specializes in a wide range of
health-promoting ingredients for the food and dietary supplement
industry. Technical information on Degussa BioActives' full
line of ingredients can be found on the web site at www.degussa-bioactives.com.
Degussa is a multinational corporation consistently aligned
to highly profitable specialty chemistry. With sales of
11.8 billion euros and a workforce of some 48,000, it is
Germany's third-largest chemical company and the world market
leader in specialty chemicals. In fiscal 2002, the corporation
generated operating profits (EBIT) of more than 900 million
euros. Degussa's core strength lies in highly-effective
system solutions that are tailored to the requirements of
its customers in over 100 countries throughout the world.
Degussa's activities are led by the vision "Everybody
benefits from a Degussa product - every day and everywhere".
Contact details:
Galapagos Genomics
Onno van de Stolpe
CEO
onno@galapagos.be
Phone: +32 15 342 900
Degussa
BioActives
Daniela Doering
Head of Communication
daniela.doering@degussa.com
Phone: +49 8161 548 150